All scientific sessions are open to all Meeting registrants. In May, the Meeting Information Pamphlet, which contains the final schedule of sessions, will be mailed to members of the sponsoring Societies, and to non-members who are authors of papers, or have registered for the Meeting, or have specifically requested a copy. The complete Program Book will be distributed only to Meeting registrants and others who specifically request a copy.

Authors of contributed papers should suggest two categories (or one category, if the paper has been invited) from the list beginning below and write their numbers on the Data Form on page 25. The Program Committee will use this information when arranging papers into coherent sessions, although the inclusion of a contributed paper into a specific listed session cannot be guaranteed. Contributed papers can be submitted toeithera planned symposium with invited speakersortooneofthegeneral areas listed. Authorsmaysuggesta categoryotherthan those listed. Contributedpapers will be assigned to a poster session if thatis the author's preference as indicated on the Data Form. Otherwise, the Program Committee will assign contributed papers to either a platform or poster session.

1. Grain Boundary MicroEngineering.

Organizers: David A.Smith & Doug Perovic.

It has been known for some years that interfaces exhibit a variation of properties which depends on their structure and composition. Only recently has it become possible to begin to engineer materials to take advantage of this behavior. The symposium on grain boundary microengineering will survey the latest developments in microscopy and microanalysis relevant to grain boundary behavior and some of their practical applications.

2. Microscopy of Modulated Structures and QuasiCrystals.

Organizers: Craig Bennett & Jim Corbett.

This symposium will highlight the application of high resolution electron microscopy, convergent beam electron diffraction, dark field imaging and scanned probe microscopies to the study of quasicrystals or modulated structures arising in low- dimensional materials, alloy phases, ceramic superconductors and ferroelectrics.

3. Frontiers in Polymer Microscopy and Microanalysis.

Organizers: Mary Buckett & Vin Berry.

This symposium focuses on new techniques and methods used for the imaging and microanalysis of polymers. This includes (but is not limited to)> advances in the scanning probe microscopies, electron spectroscopies and electron microscopies, as well as new developments in the areas of cryo-microscopy, low dose imaging, digital image acquisition, processing and analysis, and sample preparation techniques. Emphasis will be placed on the discussion and comparison of techniques and methods which probe the structural and chemical limits of these challenging materials.

4. Critical Issues in Ceramic Microstructures.

Organizers: C.Barry Carter & Jim Speck.

Many forms of microscopy are now available to study ceramic materials and the field of ceramics is itself becoming both broader and more complex. This Symposium will assess where and how the different forms of microscopy can increase our understanding of ceramics materials. Invited speakers will address such issues as industrial and processing challenges, the special features of inorganic materials and spectroscopy of ceramics. Throughout the Symposium we will emphasize the combination of new and traditional techniques.

5. Quantitative HREM Analysis of Perfect and Defected Materials.

Organizer: Manfred Ruhle.

The ultimate goal of Quantitative High Resolution Electron Microscopy of Defects in Materials is the determination of the coordinates of atoms (ions) at or close to defects. There exist different routes for a quantitative evaluation which will be discussed. The symposium will also focus on the atomistic structure of interfaces, and dislocations as well as tomographic studies of defect structures.

6. High Resolution Field Emission SEM in Materials Research.

Organizers: David Joy & Jim Pawley.

The advent of the FE gun to the SEM has made major impact to the use of instrument for high resolution studies in materials research. This symposium will consider various issues relating to instrumentation and application of these instruments to materials research.

7. Advances in Confocal and Multidimensional Light Microscopy.

Organizer: Matt Chestnut.

Covers confocal, wide-field and novel light microscopic technologies and 3-D image analysis along with their applications to biological systems. Talks will be presented on multiphoton excitation fluorescence, stimulated emission fluorescence, and other new instrument designs. Multicolor nonfocal microscopy, the automated 3-D analysis of confocal data and additional applications of confocal technology will also be discussed.

8. Correlative Microscopy in Biological Sciences: Advances and Applications.

Organizer: Ralph Albrecht.

Explores correlative microscopy and the integration of a broad range of microscopic techniques (LM, EMb AFM and SFM) for the characterization of biological materials with applications to research and clinical studies.

9. Functional Magnetic Resonance Imaging from Molecules to Humans.

Organizer Alan Koretsky.

Developments in magnetic resonance techniques now make it possible to do structure-function studies over a large distance scale from isolated molecules to human organs in a non-invasive manner. State-of-the-art lectures will illustrate the remarkable range of applications of these magnetic resonance techniques to significant problems in the biological sciences.

10. Microscopic Analysis of Animals with Altered Gene Expression.

Organizers: Susan Wert & David Witte.

Covers microscopic techniques currently used to localize foreign and endogenous gene expression in a variety of animal models. An introduction to the various marker genes used to study gene expression in transgenic animals or in response to gene transfer or replacement strategies will be provided. Techniques for the localization of mRNA and/or protein by in situ hybridization, in situ PCR, immunohistochemistry, and enzyme histochemistry will be presented, as well as morphometric techniques used to quantify tissue responses to altered gene expression.

11. New Labels in Biological Microscopy.

Organizers: Jim Hainfeld & David Spector.

This session will focus on novel Light Microscopy, Confocal, and Electron Microscopy probes. Topics will include: new fluorophores; use of green fluorescent protein fusions; low copy number in situ hybridization techniques; PCR; new gold probes; direct labeling of targeting proteins, peptides, lipids, nucleic acids and cofactors to achieve improved localizations at both the cellular and high resolution molecular levels.

12. High Resolution Biological C ryo SEM.

Organizers: Mandayam Parthasarathy & Martin Muller.

Cyro SEM is becoming a routine tool for characterization. This symposium will look at recent advances in its use in biological systems.

13. Dynamic Organization of the Cell.

Organizers: John Lemasters & Brian Herman.

Living cells are dynamic structures, constantly changing and responding to their environment. Light microscopy permits non-destructive imaging of living cells with sub-micron spatial resolution. Using parameter specific probes and a combination of new and old optical imaging techniques, a new view of the physiology of single cells is emerging. This symposium highlights the application of high resolution optical imaging techniques to problems of cytoskeletal functions in mitosis, biomechanics, membrane movement, motility and hormone-induced cell signaling.

14. Frontiers of Analytical Electron Microscopy in the Physical and Life Sciences.

Organizers:Jim Bentley & Meredith Bond.

This symposium will explore state-of-the-art analytical electron microscopy and challenges for the future, and will feature advanced techniques such as spectrum imaging, energy-filtered TEM for elemental mapping, quantitative electron diffraction, EELS fine structure, ALCHEMI, and sophisticated treatment of analytical data. Contributions are solicited on techniques or applications, especially those that stress quantitative measurements or approach detection limits.

15. High Resolution Elemental Mapping of Nucleoprotein Interactions.

Organizers: Peter Ottensmeyer & George Harauz.

The discrimination of protein from nucleic acid is an important problem in structural studies of ribosomes, nucleosomes, and many other nucleoprotein complexes. Electron microscopical approaches typically involve some form of contrast variation in the sample, or the discrimination of relative proportions of elastically and inelastically scattered electrons. This symposium will explore such methodologies with an emphasis on electron spectroscopic imaging.

16. Microbeam Mass Spectrometry.

Organizers: Susan MacKay & Scott Bryan.

The ability to acquire both elemental and molecular maps of surfaces using SIMS has revolutionized the field of microbeam mass spectrometry. This symposium will present a wide vanety of imaging SIMS applications including: cell adhesion studies; chemical mapping of polymer surfaces; and high spatial resolution surface elemental imaging. Data processing and instrumental advances will also be discussed ranging from 3D visualization methods to the addition of laser post ionization to SIMS in order to increase the achievable spatial resolution.

17. Quantitative Electron Probe Microanalysis: Fact and Fiction.

Organizers: John Small & Ian Anderson.

This symposium aims to give a critical assessment of current methods for quantitative microprobe analysis including progress in the analyses of layered structures and particles. The symposium will also consider the trends that are shaping the evolution of this technique. Contributions that address the opportunities and obstacles for soft X-ray and low voltage microanalysis are particularly solicited.

18. Molecular Microspectroscopy and Spectral Imaging.

Organizers: John A. Refner & E. Neil Lewis.

The advances in higher speed, sensitivity and resolution in Infra-Red and Raman microspectrometry have made spectroscopic imaging, microscopy and Microspectroscopy a practical reality. Using photons, these techniques probe molecular chemistry at the microscopic scale. This symposium highlights the enormous impact that these emerging technologies have for analytical microscopists.

19. Microanalysis Applications in XRD and XRF.

Organizer: Michael Eatough.

Total reflection collimators have enabled analysts to perform x-ray diffraction and x-ray fluorescence analysis on areas as small as 5 micrometers. This session will cover the history of micro x-ray analysis, the use of total reflection collimators and applications using this relatively new analysis technique.

20. Compositional Imaging in Biology - Assessment and Validation.

Organizer: Dale E. Johnson.

This symposium will discuss the importance of, as well as methods for, the quantitative assessment and validation of compositional images. The emphasis will be on the analysis of elemental images of biological specimens generated using electron energy loss data in either the STEM or the TEM.

21. The Challenges of Generating and Displaying Images with Emerging Technologies.

Organizer: Margaret Ann Goldstein.

The presentations in this session will explore how the generation and display of images and the communication by images has and will be changed using today's modern technology

22. Scanning Probe Microscopy: Instrumentation and Applications in Biological and Physical Sciences.

Organizers: Inga Musselman & Phil Russell.

This symposium will highlight recent developments and advances in instrumentation and applications in scanning probe microscopy including atomic force microscopy, scanning tunneling microscopy/spectroscopy, and related proximal probe based technologies. Novel applications of scanning probe techniques ranging from biological studies, materials microstructural evaluations, and metrology to commercial research and quality control will be highlighted.

23. Applications of Leaky (Low Vacuum/ Environmental) SEM.

Organizers: John F. Mansfield & Stuart McKernan.

Whether we call our instruments ESEMs, Wet SEMs, Low Vacuum SEMs, "Leaky Vacuum" SEMs or even "Lousy Vacuum" SEMs, we are all Environmental Scanning Electron Microscopists. The field of Environmental Scanning Electron Microscopy has now become well established, particularly because these instruments have the unique capability of forming secondary or back-scattered electron images, while the sample is in what would typically be considered an extremely poor vacuum. The sample chambers are typically quite large and can accommodate a wide variety of experimental platforrsls for in situ observation. Such specializedin situ systems include high temperature stages, cold stages, uniaxial straining and multi-point bending stages and liquid sample stages. This symposium will focus on materials science and biological science applications in these Environmental Scanning Electron Microscopes.

24. TelePresence Microscopy in Education & Research.

Organizer: Nestor J. Zaluzec.

Advances in digital technology have brought us to the regime where we can now realistically transmit commands, text, images, and voice in near real time over high speed communications interfaces. Using these methods it is now practical to consider on-line remote access and control of scientific instrumentation over networks. In this symposium we will explore the present status and future prospects of these operating modes for use by the Microscopy and Microanalysis community applied to both education and research environments.

25. Image Analysis in the Physical and Biological Sciences.

Organizers: Gilles L'Esperance & Carmen Mannella.

This symposium will highlight progress being made in computer analysis of images of biological and physical specimens, with particular emphasis on data from transmission electron microscopy. Speakers will describe the increasingly sophisticated computational techniques being used to derive accurate information from noisy images of objects present in single or multiple representations including lowdose and low-contrast images. The symposium will also cover strategies (commonly used in biological applications) to reconstruct the three-dimensional structure of objects from projection data, as well as microstructural features typical of materials science problems .

26. Tech Forum: Moving to Digital Microscopy - Is the Time Right?

Organizer: Sandra H. Silvers.

This symposium examines basic concepts that a laboratory will need to consider to facilitate the move from film based to digital technologies, including: current state-of-the-art, ethics of digitization, and applications. After an associated poster session in the afternoon, the symposium will conclude with "Platform Wars" - a lively discussion of Mac-based vs. DOS/ Windows-based vs. UNIX-based digital systems.

27. Amorphous/Structurally Disordered Phases
28. Catalysts
29. Ceramics
30. Coatings
31. Electronic Materials
32. Environmental Problems
33. Geology/Mineralogy
34. In Situ Experiments
35. Magnetic Materials
36. Materials Science
37. Materials Technology
38. Metals & Alloys
39. Nanophase Systems
40. Oxidation & Corrosion
41. Petrology
42. Phase Transformers
43. Polymers
44. Radiation Sensitive Materials
45. Small Particles, Clusters
46. Superconductors
47. Surfaces & Interfaces
48. Tribology
49. Other Physical Science Areas

50. Chemical
51. Electrochemical
52. Mechanical
53. Sputtering

54 Biological Probes
55. Biological Ultrastructure
56. Biomedical Applications
57. Biomedical Imaging
58. Cell Biology
59. Cell Death
60. Cell Signalling
61. Cell Surface
62. Chromosomes & Nuclei
63. Correlative Microscopy
64. Cryotechniques
65. Cytoskeleton
66. Cytochemistry/Histochemistry
67. Developmental Biology
68. Diagnostic Imaging
69. Extracellular Matrix/Cell- EC M Interactions
70. Forensic Science
71. Gene Therapy
72. Genetic Analysis
73. Immunocytochemistry
74. Immunology
75. In Situ Hybridization
76. Macromolecular Microscopy
77 Membranes & Transport
78. Microbiology
79. Muscle
80. Neurobiology
81. Organelles
82. Pathology - Experimental,Diagnostic, Forensic
83. Pharmacology
84. Plant Biology & Pathology
85. Reproductive Biology
86. Specimen Preparation & Labeling
87. Telemedicine
88. Toxicology
89. Other Biological Applications

90. Cyro Preparation SEM/TEM
91. Colloidal Gold
92. Frozen Hydrated Specimens
93. Probes/Labels

94. Acoustic Microscopy
95. Analytical Electron Microscopy
96. Ancillary Equipment
97. Charged Particle Instrumentation
98. Confocal Microscopy
99. Developments in Computer Controls
100. Electron-Optical Instrumentation
101. Field Emission Technology
102. Image Recording Technologies
103. Light-Optical/Video Instrumentation
104. Microscopy Education
105. Microscopy Resources
106. Near Field Instrumentation
107. New Commercial Instrumentation
108. Scanning Electron Microscopy
109. Scanning Probe Instrumentation
110. Scanning Transmission Electron Microscopy
111. TelePresence Microscopy
112. Transmission Electron Microscopy
113. Two Photon Microscopy
114. Video Microscopy
115. X-ray-Optical Instrumentation

116. Energy Filtered Imaging
117. General Optics
118. High Resolution SEM
119. High Resolution TEM/STEM
120. Image Contrast Formation
121. Optical & Electron Holography
122. Optical & Near Field
123.Scanning Probe

124. Convergent Beam
125. Conventional Diffraction Techniques
126. Energy Filtered Diffraction
127. Electron Channeling
128. X-ray & Optical Crystallography

129. Auger Electron Spectroscopy
130. Computational Methods
131. Electron Energy Loss Spectroscopy
132. Energy Filtering Spectroscopy
133. Image Processing, Analysis & Modeling
134. Microbeam Mass Spectroscopy
135. Optical Microspectroscopies
136. Stereology
137. Surface Analysis Methods
138. Tomography - 3D Reconstruction
139. Tomography - Morphometry
140. X-ray Energy Dispersive Spectroscopies - Bulk
141. X-ray Energy Dispersive Spectroscopies - Thin Film
142. XRF/XRD Techniques